SearchLight DNA™ delivers tangible clinical benefits that directly impact your ability to provide optimal care for your canine cancer patients. Beyond standard diagnostics, SearchLight DNA empowers you to with improved diagnostic accuracy in challenging cases, allows you to make more informed treatment decisions based on a deeper understanding of tumor behavior, and can identify potential therapeutic targets, providing additional treatment options for your patients.
Flexible Sample Options for Every Case
SearchLight DNA can be run from common samples, no special treatment is needed
FNA Slides
FNA Liquid
FFPE Scrolls
Unstained FFPE Slides
Bony Tumor
Clinical Benefits of SearchLight DNA
Improve Diagnostic Accuracy
Many cancers are recognizable to the trained pathologists and oncologists, but not all cancers. Sometimes the mutations in a cancer can guide diagnosis, which is a key part of understanding what that tumor will do in the body.
Empower Informed Decisions
SearchLight DNA offers precise and accurate identification of DNA mutations, enhancing our understanding of a tumor’s potential behavior. This knowledge is crucial for guiding pet families and veterinarians as they navigate the uncertainties of cancer. By providing detailed insights, SearchLight DNA helps create the most effective and personalized treatment plans for each unique patient and their family.
Identify Therapeutic Targets
In human oncology, hundreds of safe and effective precision therapies target specific cancer mutations. While fewer precision therapies currently exist in veterinary medicine, SearchLight DNA is paving the way for their development. By identifying therapeutic targets in pet cancers, SearchLight DNA helps us understand which human drugs can be repurposed for veterinary use today and anticipates the future availability of more targeted treatments for pets.
Where SearchLight DNA shines
Cases
Example
Poorly differentiated tumors
Undifferentiated round cell tumors
Tumors with an uncertain diagnosis
Amelanotic melanoma vs oral sarcoma
Tumors in uncommon locations
Mammary melanoma or retropharyngeal hemangiosarcoma
Tumors in which a standard of care does not currently exist
Splenic liposarcoma
Tumors in which there are no effective chemotherapy treatment options
Metastatic hemangiosarcoma
Tumors that have progressed despite standard-of-care treatment
Apocrine gland anal sac adenocarcinoma with local or distant progression
Metastatic lesions in unexpected or uncommon locations
Thyroid carcinoma that metastasized to the spleen
Thyroid carcinoma that metastasized to the spleen
Pet owners who do not want to pursue injectable chemotherapy, preferring oral therapy options
What you get with SearchLight DNA
Diagnostic, Prognostic, and
Therapeutic biomarkers*
Targeted
therapeutic drug(s)
Drug Monographs
One on One Consult with
Board Certified DVM
*Not all tumors sequenced will contain biomarkers or be a match for Targeted Therapeutics
Frequently Asked Questions
Everything you need to know about SearchLight DNA
Are international orders accepted?
Yes, we accept international orders! Before setting up an account with us, you must be able to pay invoices in USD, maintain responsibility for packaging and shipping samples internationally, and can confirm your billing contact information. If these terms are acceptable, place your order through our website which will automatically generate an account.
What needs to be submitted to run SearchLight DNA?
View SearchLight Sample Requirements PDF
SearchLight DNA can be run on samples submitted in the following forms (and quantities)
- Fine Needle Aspirate Slides (>5 unstained or stained slides) with one Diff-Quick slide
- FFPE Scrolls (10 x 10-micron sections) with 1 adjacent H&E slide
- Unstained FFPE Slides (10 x 10-micron sections) with 1 adjacent H&E slide
- Decalcification of bone tumors (including osteosarcoma) often involves strong acids that can destroy DNA. If you are submitting a bony tumor for SearchLight DNA it is important that we obtain a sample that has not undergone decalcification in strong acid. Please submit a non-decalcified sample or allow us to coordinate with the pathology lab in order to determine if SearchLight DNA is feasible for that sample.
When should I order SearchLight DNA?
Searchlight DNA can be ordered at the time of tumor sampling (aspiration or biopsy) or after results/cytology is returned. Searchlight DNA can aid in diagnosis, prognosis, and/or treatment planning. It may help guide you in cases where treatment protocols are unclear/borderline, or in cases where the veterinary team desires more data before recommending a course of treatment. Identification of predictive genomic biomarkers associated with targeted therapies, description of the context in which those therapies may be effective, and provision of the evidence to support those associations can assist you in considering integration of targeted therapies into treatment protocols. It may also help guide you in cases that have ambiguous or unclear histopathology. When a patient’s disease progresses amid therapy or when a new metastatic lesion displays unexpected or bizarre behavior, Searchlight DNA can help identify new mutations that could provide additional biomarker associations to inform a patient’s evolving clinical management. Searchlight DNA can help inform clinical decision-making in these cases, but every case is unique and other cases in which this test is helpful may exist. To talk with someone at Vidium to determine if Searchlight DNA is right for your patient, please contact us.
What is the expected turnaround time?
Reports for SearchLight DNA tests are delivered 9-12 days from receipt of the sample at the Vidium genomics laboratory.
Will there be someone for me to talk to about the SearchLight DNA report?
Yes. We understand that it may be helpful to discuss the report with our scientists, so we offer one-on-one phone consultations for veterinarians following delivery of your SearchLight DNA report, free of charge.
For pathology cases, please contact your pathologist directly using the contact information in your report.
How do I order SearchLight DNA?
SearchLight DNA is available directly through here. Simply fill out the order form and we’ll handle the rest.
For Antech customers, you can now add-on SearchLight DNA to your existing pathology order by calling Antech Customer Service at 1-800-872-1000. Antech will ship your sample to Vidium for testing and a report will be returned via Antech report delivery methods.
Still have questions?
Schedule a one-on-one consultation with our veterinary specialists to discuss specific cases and explore how our genomic insights can enhance your treatment strategies.